| Accession | HsInv0744 | Region of the inversion | chr11:104435827-104481271 |
| Status | Unreliable prediction | Prediction type | Simple |
| Estimated Inversion Size | 33,696 bp | Supporting predictions | 1 |
| Inverted allele frequency | ND | Mechanism of origin | ND |
| Functional effect | Intergenic breakpoints | Breakpoint 1 | chr11:104435827-104456108 |
| Ancestral orientation | NA | Breakpoint 2 | chr11:104478054-104481271 |
|
|
 |
|
|
Human Polymorphic Inversion DataBase
|
General information
- Region map
+ Predictions
- Martinez-Fundichely et al. 2014 (in preparation)
| Description | Accurate prediction of inversions in the human genome from Kidd et al. 2008 fosmid paired-end mapping data using the GRIAL algorithm, and validation of some predictions by sequence analysis and PCR | ||||||||||||||||||||||||||||||||||||||||||
| Method | Paired-end mapping (PEM) | ||||||||||||||||||||||||||||||||||||||||||
| Name | |||||||||||||||||||||||
| Breakpoint 1 | chr11:104435827-104456108 | Breakpoint 2 | chr11:104478054-104481271 | ||||||||||||||||||||
| D/C Score | -0.94 | Disc. Support Prob. | 0.00004 | ||||||||||||||||||||
| Support | 7 probes  | ||||||||||||||||||||||
| Individuals |
| ||||||||||||||||||||||
| Comments | Analysis of fosmids supporting the inversion indicates that all of them have one end-read mapping in same region caused probably by misspriming of sequencing primer inside the fosmid. Below the threshold of the Discordant Support (DS) probability | ||||||||||||||||||||||
+ Validation and genotyping
No validations are found
+ Frequency
No frequency studied
+ Breakpoints
| Breakpoint 1 | chr11:104435827-104456108 | Breakpoint 2 | chr11:104478054-104481271 | |||||||||||||
| Definition method | Default informatic definition | |||||||||||||||
| Mechanism of origin |
ND
|
|||||||||||||||
| Flexibility | 11.97 | GC content | 0.32 | Stability | 1.76 |
| Position SD1 | Size (bp) | Position SD2 | Size (bp) | Identity | Relative orientation |
| chr11:104440299-104470272 | 29,974 | chr11:104470278-104500455 | 30,178 | 0.915 | Direct |
+ Evolutionary history
| Ancestral allele | NA | Age | ND |
| Derived allele | NA | Origin | ND |
+ Orientation in other species
Not defined
+ Age
Not defined
+ Origin
Not defined
+ Functional effects
No genes disrupted by the inversion breakpoints
+ Inversion phenotypical effects
Not defined
+ Report history
- 2015-02-23 10:14:26
| Breakpoint 1 | chr11:104435827-104456108 | Breakpoint 2 | chr11:104478054-104481271 |
| Assembly | hg18 | ||
| Definition method | Default informatic definition | ||
